The total revenues for the fourth quarter of 2011 declined 7% to $1.47bn from $1.58bn a year ago.
Net interest income, on a taxable equivalent basis, was $920m, compared to $919m for the same period in the last year.
For the full year, Fifth Third reported a net income of $1.1bn, or $1.18 earnings per diluted share, compared to $503m, or $0.63 earnings per diluted share, for the same period in 2010.
Fifth Third Bancorp president and CEO Kevin Kabat said that the fourth quarter saw a significant pick-up in demand and loan growth, with end of period total loan growth of 2 percent, including 5 percent in C&I lending which continues to be a strength for them.