The job cuts would be achieved through layoffs across the bank’s global investment banking operations.
Barclays plans to close its investment banking businesses in Australia, Indonesia, Malaysia, Philippines, South Korea, Taiwan and Thailand, Reuters reported.
The bank will, however, continue to operate in Hong Kong, China, Japan, Singapore and India, and keep its prime brokerage and derivatives business in Asia, The Guardian reported.
The move will also have an impact on its operations across central and eastern Europe, and South America.
The job cuts are in response to the current uncertainty in global equities and commodities markets, according to Reuters.
The latest move to reduce workforce is in addition to the 19,000 cuts announced by the bank new CEO Jes Staley in his three-year cost reduction plan.
Staley was quoted by The Guardian as saying: "With these actions, we are accelerating the investment bank strategy outlined in 2014, focusing on its core strengths and running the business for returns.
"We continue to build on the business’s dual home markets in the UK and US and remain committed to a strong presence in Asia and EMEA, consistent with operating a leading global investment bank within the Barclays group."