The technology will be rolled out in two phases and will be compatible with the Santander iOS smartbank app.
The first phase will allow customers to talk to their mobile banking app and ask about their card spending.
Phase two, which is due for release later this year, will enable customers to service their accounts using only their voice.
It includes advanced features like the ability to make payments, report lost cards, establish account alerts and answer a range of questions about spend.
Santander said the technology can also be a useful tool for vulnerable customers who chose to bank from home and find speaking easier than typing or using online banking.
Santander UK CEO Nathan Bostock said: "Technology is rapidly changing how customers bank and pay on the move.
"We want banking to be simple, personal and fair and we believe technology, like voice banking, will play a transformational role in the way we add value by creating more choice and convenience for our customers."
Santander UK provides a range of personal and commercial financial products and services.
It serves over 14 million active customers with 20,000 employees and operates through 857 branches and 70 regional corporate business centers.
Image: Santander UK head office, Triton Square, London. Photo: courtesy of Elliott Brown from Birmingham, United Kingdom.
